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The next paragraph underlines the essential roles in the immunomodulation of B vitamins

PFOS exposure disrupts intestinal barrier function and interferes with key proteins and signaling pathways [226], BPA and its alternatives disrupt glucose-lipid metabolism and induce inflammatory responses [227]

In the HS model, both protein misfolding and excessive production of reactive oxidative species (ROS) can stimulate this stress response [50, 51]

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Curcumin, a potent phenolic compound, exhibits various physiological effects, including anti-inflammatory, antioxidant, and anti-tumor properties